An important concern of the diagnosis of contact allergy to certain substances is the possibility of implanting a foreign body that contains material to which the patient is allergic. For example no one is exempt from needing an orthopedic surgery after a fracture. If for example the patient has a known nickel allergy and during the surgery a screw containing nickel is used, then a rejection of the screw will follow resulting in the absence of bone healing and an unwarranted surgery to remove the screw and replace it with suitable material.
Therefore, patients in whom contact allergy is diagnosed should always inform their physicians about the allergy, especially before the implantation of any foreign body.