Allergic diseases that involve the skin, such as atopic dermatitis - allergic eczema, contact dermatitis, chronic allergic rashes (chronic urticaria) may lead to irreversible changes in the involved skin due to a direct deleterious effect or due to an indirect effect (secondary to treatment), for example:
- Thickening of the skin.
- Changes in skin color.
- Fragile skin with easy subcutaneous bleeding and a propensity to wounds.
- Premature aging of the skin.